DNA molecule-mediated metal plasma nanostructure research progresses

DNA molecule-mediated metal plasma nanostructure research progresses

Metal nanostructures generate specific surface plasmon resonances when interacting with light. This kind of plasmonics based on metal nanostructures has a wide range of applications in biosensing, bioimaging, photocatalysis and solar cells.

Recently, the Institute of Applied Physics, Shanghai Institute of Applied Physics, Institute of Applied Physics, Fan Chunhai Group, and Shanghai Light Source Chen Gang's Research Group have used DNA molecules to precisely control the growth of Au nanoplasma structures and use synchrotron X-ray small-angle scattering (SAXS). The technique reveals the mechanism of DNA-mediated nano-gold growth and establishes a semi-quantitative relationship between nano-gold structure and its surface plasmon resonance properties. The related results were recently published in "Angew. Chem. Int. Ed. 2014, 53, 8338-8342".

Gold nanoparticles have excellent properties in biological detection, chemical catalysis and nanophotonics, and their physical and chemical properties are highly dependent on their size and surface morphology. Therefore, how to fine-tune its structure at the nanoscale has attracted the attention of researchers.

DNA molecules are generally known as carriers of genetic information. However, the precise coding of DNA molecules can also provide new ideas for the field of materials. Due to the strong interaction between DNA and gold surfaces, Shen Jianlei, a graduate student of Shanghai Yingwu University, tried to use DNA to regulate the growth of the gold nanoplasma structure, and obtained a precise structure of the nanogold structure.

They used the SAXS technology from the Shanghai BL21B1 station to perform in situ characterization of the different growth stages of the golden flower, and combined with the TEM to obtain the fine structure of the product during the growth of the nanogold flower under DNA regulation. Based on this, the mechanism of the growth of DNA structure mediated by DNA molecules was revealed. Using the obtained structural parameters, combined with experiments and optical simulations, the fine structure and local surface plasma of nano-gold flower were established. The semi-quantitative relationship of body (LSPR) characteristics. Further studies have shown that these nano gold flower plasma structures exhibit significant surface Raman enhancement (SERS) and dark field scattering (Dark-Field Scatter) properties, and are expected to become highly sensitive bio-imaging probes.

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