Core Tip: Fats in snacks will stimulate unexpected biological reactions in the body and may lead to overeating. Irving researchers at the University of California, USA, found that the culprit was a chemical similar to cannabis that was naturally produced in the human body and was called endocannabinoid.
The endogenous cannabinoids in human cells are the real reason why we couldn't stop eating chips.
If you taste a French fries or a piece of potato chips, few people can control themselves without sweeping away the remaining French chips. Why is this? Recently scientists have finally figured out why people couldn’t stop unhealthy foods—naturally occurring cannabis in the body.
Fats in snacks can excite unexpected biological reactions in the body and can lead people to overeating. Irving researchers at the University of California, USA, found that the culprit was a chemical similar to cannabis that was naturally produced in the human body and was called endocannabinoid.
The study found that if mice were fed high-fat foods, their upper gastrointestinal tract cells began to secrete endocannabinoids. Giving them sugar or protein foods does not produce this phenomenon.
This process began with the tongue. The tongue tastes the fat in the food and sends a reflected signal to the brain. The brain sends information through the vagus nerve to the intestines. Daniel Piomali, research director, said that the signal transmitted to the stomach stimulated the mass production of endocannabinoids, causing people to suddenly want to eat more high-fat foods. Endogenous cannabinoids begin to release digestive substances that make people feel hungry, so people want to eat more.
Professor Pyomaili said that from an evolutionary point of view, there are few opportunities in nature to obtain natural fats, but fats are also crucial to maintaining the normal function of cells. Therefore, when animals come into contact with fatty foods, they have a physical instinct. We have issued a strong order to eat a big meal. However, for humans, fat foods are no longer a rarity. Instincts such as high-oil, high-fat foods that secrete cravings for lust hormones have increasingly triggered diseases such as obesity, diabetes, and cancer.
The results of this research may help people find ways to solve this problem - for example, blocking the transmission of addictive signals by using drugs to control the cell's reception of endocannabinoids. Professor Pyomaly said that if one blocks the endocannabinoid in the brain, people will feel anxiety and grief, but this drug actually acts outside the brain, so it will not cause the aforementioned side effects. .
The research results were published in the "American Academy of Sciences."
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