Anti-heat stress effect of arginine on livestock and poultry

The role of arginine and its metabolites in the body Keb China Feed Industry Information Network - based on feed, serving animal husbandry

1 The role of NO pathway in arginine in the cardiovascular system Keb China Feed Industry Information Network - based on feed, serving animal husbandry

The study found that the L-arginine-NO pathway is very important. NO is a very strong diastolic vascular substance (Radomski et al., 1991) and plays an important role in maintaining constant vascular tone and regulating blood pressure stability. L-arginine is a precursor of NO production. L-arginine supplementation promotes NO production and promotes vasodilation and angiogenesis. On the contrary, L-arginine deficiency leads to a decrease in NO production, which in turn affects angiogenesis. And development. Studies have shown that NO plays a role in the cardiovascular system by activating cytosyl cyclase (GC) in cells and increasing the concentration of cyclic guanosine monophosphate (cGMP) to accomplish various physiological functions such as vasodilation (XIAO Libo et al. 2009). Keb China Feed Industry Information Network - based on feed, serving animal husbandry

2 arginine NO pathway and regulation of immunity Keb China feed industry information network - based on feed, service animal husbandry

There are many ways in which arginine affects immune function, but it is mainly achieved through the arginine-NO pathway and the regulation of endocrine hormones. It plays an important role in regulating body immunity and intestinal mucosal function protection. Arginine also promotes the production of immunoglobulins and effectively enhances humoral immunity. Arginine is the only substrate for the synthesis of NO, which synthesizes NO under the catalysis of NOS. NO is an important immunoregulatory factor, and its regulation of the immune system mainly includes (Li Xia et al., 1996): 1 regulates T lymphocyte proliferation and antibody response, inhibits mast cell reactivity; 2 regulates T cells and giant The phagocyte secretes cytokines; 3 promotes the activity of natural killer cells, activates monocytes in peripheral blood; 4 mediates apoptosis of macrophages. In addition, NO can relax gastrointestinal smooth muscle, regulate gastrointestinal mucosal blood flow, thereby maintaining mucosal integrity, maintaining gastrointestinal mucosal barrier function; also inhibiting leukocyte migration to the injury site, while reducing intestinal mucosal permeability, thereby reducing the intestinal tract Mucosal damage. Studies have shown that dietary supplementation with arginine enhances the immunity of pregnant sows and newborn piglets, thereby reducing morbidity and mortality in piglets (Jobgen et al., 2006). Keb China Feed Industry Information Network - based on feed, serving animal husbandry

3 arginine in the role of endocrine Keb China feed industry information network - based on feed, service animal husbandry

Arginine can stimulate the body to secrete growth hormone and insulin. Arginine is metabolized to produce ornithine, which in turn produces glutamate, both of which promote the body's release of growth hormone. In addition, NO synthesized by arginine under NOS catalysis can also promote the release of growth hormone. Arginine can also stimulate the release of insulin from humans and other mammals including pigs, cattle and sheep. Growth hormone and insulin play an important role in the metabolism of sugars and proteins in the body tissues. Keb China Feed Industry Information Network - based on feed, serving animal husbandry

4 The role of arginine in anti-oxidative stress Keb China Feed Industry Information Network - based on feed, serving animal husbandry

L-arginine is a free radical scavenger of the body (Jiang et al., 2000). NO is a catalyzed reaction between L-arginine and molecular oxygen. It is a novel cell information molecule with dilated blood vessels and platelets. Aggregation, inhibition of cell proliferation, inhibition of lipid peroxidation and formation of glycosylation end products (Xiong et al., 1994). In general, NO exerts beneficial physiological effects in small doses. In large doses, it often causes disease or worsens the condition (Yue Xu et al., 2002), and an appropriate amount of NO can scavenge oxygen free radicals (Beligni et al. , 2002; Wink et al., 2001). In recent years, a large number of studies have been conducted on the application of L-arginine in the prevention and treatment of free radical damage in rats. Supplementation of L-arginine in rats can increase the activity of antioxidant enzymes, reduce the content of malondialdehyde (MDA), and reduce oxidation. Stress damage to rats (Huang et al, 2009; Lin et al, 2008), improve the body's antioxidant capacity. Supplementation of L-arginine can promote the production of NO, and increase the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in tissues, and reduce the content of MDA, indicating that it is refined. Oxygen supplementation of NO can significantly reduce oxidative stress in rats. The anti-oxidative stress of L-arginine in vivo is mainly achieved by the L-arginine-NO pathway (Le Kangfu et al., 2005; Trisha, 2006; Assumpcao et al., 2008). Keb China Feed Industry Information Network - based on feed, serving animal husbandry

Keb China Feed Industry Information Network - based on feed, serving animal husbandry

Low voltage pvc insulated electric wire has been widely used in our country with the advantages of excellent electric properties, strong ability to resist short circuit, long service life , easy to install, operate and maintain, etc      

     The product of low voltage stranded pure copper 2.5mm 6mm electric cable  belong to the series of laying electric wires,  which is mainly suitable for laying at the fixed places,  It is widely used as connectors of drive, lighting , electronic equipments  , Instrument and telecommunication equipments with rated voltage 450/750v or below ,  Part of plastic wires are used at the equipment with A.C rated votage 300/300v or below.

Standards:     ASTM / ICEA S-76-474 , IEC 60502 ,DIN,  NFC 33-209 , BS 7870 GB/T 12527 etc

Nominal section.(mm2) conductor No./Dia (mm) Insulated thick (mm) Max.overall Dia. (mm) Conductor resistance at 20'C Weight (kg/km)
copper aluminum copper aluminum
1.5 1/1.38 0.7 3.3 12.1   19.2  
2.5 1/1.78 0.8 3.9 7.41 11.8 30.8 15.0
4 1/2.25 0.8 4.4 4.61 7.39 45.5 21.0
6 1/2.76 0.8 4.9 3.08 4.91 65.0 29.0
10 7/1.35 1.0 7.0 1.83 3.08 110.0 52.0
16 7/1.70 1.0 8.0 1.15 1.91 170.0 70.0
25 7/2.14 1.2 10.0 0.727 1.20 270.0 110.0
35 7/2.52 1.2 11.5 0.524 0.868 364.0 150.0
50 19/1.78 1.4 13.0 0.387 0.641 500.0 200.0
70 19/2.14 1.4 15.0 0.268 0.443 688.0 269.0
95 19/2.52 1.6 17.5 0.193 0.320 953.0 360.0
120 37/2.03 1.6 19.0 0.153 0.253 1168.0 449.0
150 37/2.25 1.8 21.0 0.124 0.206 1466.0 551.0
185 37/2.52 2.0 32.5 0.099 0.164 1808.0 668.0

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