Porcine circovirus infection is a new infectious disease in pigs caused by porcine circovirus. The disease can cause severe immunosuppression in the herd, which can easily lead to secondary or concurrent infectious diseases. _
At present, the disease has spread throughout the world of pig raising countries and regions. China was first discovered in 2001. At present, the disease has been widely spread in pigs in China, causing huge losses to the pig industry. Porcine circovirus disease has become a new infectious disease that seriously harms the world's pig industry.
It is only the main host of porcine circovirus (PVC). Pigs have a strong susceptibility to PVC, and pigs of all ages can be infected, but piglets are seriously ill after infection. Pigs that are infected during embryonic or early postnatal period can often develop after weaning, generally concentrated at 5-18 weeks of age, especially at 6-12 weeks of age. When pregnant sows are infected with PVC, they can be transmitted vertically to the piglets via the placenta and cause reproductive problems. Infected pigs can eliminate viruses from nasal fluids, feces and other wastes, and cause infections through the digestive tract and respiratory tract.
Serological survey found that the foreign pig population PVC positive rate of 20% -80%, the domestic positive rate also reached 52.8% -100%.
Since the discovery of PVC, PVC-1 and PVC-2 have been proven to be worldwide prevalent and existing viruses. Among them, the infection of PVC-2 virus in pigs in China has been quite serious.
The virus is a necessary factor for the disease, but it is not a sufficient condition. It must be accompanied by other factors to lead to obvious and serious clinical diagnosis. These factors, besides some common and important pathogens, include poor management and management. Poor ventilation, temperature discomfort, vaccination stress, polyculture of pigs of different origins and ages. The incidence and mortality of this disease vary greatly, depending on the health status of the herd, feeding management level, environmental conditions and virus type, etc., generally 10%-20%, individual morbidity and mortality can reach 40%.
Pig disease symptoms:
The porcine circovirus infection has a long incubation period, even after the embryonic or early postnatal infection, the symptoms appear after the weaning. PVC-2 infection can cause a variety of conditions:
1. Multi-systemic exhaustion syndrome after pig weaning 2 l
It usually occurs in weaned piglets and was first reported in 1997, followed by reports from the countries of the Americas, Europe and Asia. It has been confirmed that PVC-2 is an important pathogen of multi-systemic exhaustion syndrome after pig weaning. Mixed infection and immune stimulation of pathogens such as reproductive and respiratory syndrome virus, parvovirus and pseudorabies virus can aggravate the degree of harm of the disease.
The pigs showed poor mental health, loss of appetite, slightly higher body temperature, weak muscle weakness, diarrhea, difficulty breathing, eyelid edema, jaundice, anemia, weight loss, poor growth and development, and the body weight of the same age pig was very different, skin eczema, systemic Lymph node lesions, especially in the inguinal, mesenteric, bronchial and mediastinal lymph nodes, the incidence rate is 5% - 30%, the mortality rate is 5% -40%, the rehabilitation pig becomes a stiff pig.
2. Dermatitis and nephrotic syndrome;
Pigs usually occur in 8-18 weeks of age. It was first reported in the UK in 1993 and subsequently reported in the United States, Europe and South Africa, and Asia. The incidence rate is 0.15% - 2%, and sometimes up to 7%. Irregular plaques with reddish purple ridges in the perineum and limbs are the main symptoms. Pigs present with subcutaneous edema, loss of appetite, and sometimes elevated body temperature. Usually die within 3 days, sometimes for 2-3 weeks.
3. Proliferative necrotizing interstitial pneumonia.
This disease mainly affects pigs aged 6-14 weeks. The incidence rate is 2%-30%, and the mortality rate is 4%-10%.
4, reproductive disorders
Lead to increased sows, miscarriage, abortion, stillbirth and weak births.
Pig disease prevention and treatment:
Because there is no effective vaccine for the prevention of PVC-2 infection in the world, the main measures to control PVC-2 infection include: strengthening environmental disinfection and feeding management, reducing piglet stress, and doing pseudorabies, pig breeding and respiratory system. Comprehensive prevention and treatment of other diseases such as syndrome, parvovirus disease, asthma, infectious pleuropneumonia, etc. If necessary, try your own inactivated vaccine to prevent it.
Regular addition of antibiotics such as Zhiyuanjing, chlortetracycline, and amoxicillin to the feed may have a role in preventing the disease or reducing the incidence, mainly because it inhibits some common bacterial pathogens in the herd. Enhanced herd resistance. It is best to eliminate the diseased pigs, and those who cannot be eliminated can use the above drugs together with symptomatic treatment to reduce the mortality rate. (Transfer from a long time information network: http://)
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